Recombinant Human GM-CSF Protein

Catalugue Number: GMP-GW302-0100

Filling Volume: 100μg

Stock: In Stock

Product Information

Cytokines-Recombinant Human GM-CSF Protein
Product Name	Recombinant Human GM-CSF Protein
Expression Host	HEK293 cells
Synonyms	GM-CSF,CSF2,MGC131935
Protein sequence	NP_000749.2: A18-E144 expressed with a His tag at the C-terminus
Molecular weight	The predicted theoretical molecular weight is 15.3 kD
Purity	> 90%, analyzed by SDS-PAGE gel
Endotoxin	< 0.1EU/ μg
Biological activity	Cell proliferation assay using TF-1 cells, activity ≥5.0×10⁶ IU/mg
Purification method	Chromatographic purification
Appearance	White loose body
Intended Use	GM-CSF is a hematopoietic growth factor that can stimulate the colony formation of neutrophils and macrophages in vitro and has the function of promoting the proliferation and development of early erythroid megakaryocytes and eosinophilic progenitor cells. GM-CSF is one of the earliest cytokines identified to have an effect on DC. The function of GM-CSF in DC culture is to promote the differentiation of monocytes into macrophage-like cells, increase the expression of MHC class II molecules on the cell surface, and thus enhance the antigen presentation function of the cells. In addition, GM-CSF can also promote the survival of DCs. Suitable for the production of cell therapy products.
Instructions	Freeze-dried preparations can be stored at -20 °C If aliquoting is required, it can be dissolved with water for injection, saline, culture medium or PBS, and then aliquoted into small portions. The storage period is 6 months at -20 ℃ and 12 months at -80 ℃. The concentration after dilution should not be less than 100 μg /mL. Avoid repeated freezing and thawing.